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CORTICOSTEROIDS Medium to Very High Potency (Topical)

Some frequently used brand names are:

In the U.S.—

  • Alphatrex 3
  • Aristocort 20
  • Aristocort A 20
  • Betatrex 3
  • Beta-Val 3
  • Bio-Syn 9
  • Cordran 11
  • Cordran SP 11
  • Cormax 4
  • Cutivate 12
  • Cyclocort 1
  • Delta-Tritex 20
  • Dermabet 3
  • Dermatop 19
  • Diprolene 3
  • Diprolene AF 3
  • Diprosone 3
  • Elocon 18
  • Florone 7
  • Florone E 7
  • Fluocet 9
  • Fluocin 10
  • Fluonid 9
  • Flurosyn 9
  • Flutex 20
  • Halog 13
  • Halog-E 13
  • Kenac 20
  • Kenalog 20
  • Kenalog-H 20
  • Kenonel 20
  • Licon 10
  • Lidex 10
  • Lidex-E 10
  • Locoid 15
  • Luxiq 3
  • Maxiflor 7
  • Maxivate 3
  • Olux 4
  • Pandel 16
  • Psorcon 7
  • Synalar 9
  • Synalar-HP 9
  • Synemol 9
  • Teladar 3
  • Temovate 4
  • Temovate E 4
  • Temovate Scalp Application 4
  • Topicort 6
  • Topicort LP 6
  • Triacet 20
  • Triderm 20
  • Ultravate 14
  • Uticort 3
  • Valisone 3
  • Valisone Reduced Strength 3
  • Valnac 3
  • Vanos 10
  • Westcort 17

In Canada—

  • Aristocort C 20
  • Aristocort D 20
  • Aristocort R 20
  • Beben 3
  • Betacort Scalp Lotion 3
  • Betaderm 3
  • Betaderm Scalp Lotion 3
  • Betnovate 3
  • Betnovate-1/2 3
  • Celestoderm-V 3
  • Celestoderm-V/2 3
  • Cyclocort 1
  • Dermovate 4
  • Dermovate Scalp Lotion 4
  • Diprolene 3
  • Diprosone 3
  • Drenison 11
  • Ectosone Mild 3
  • Ectosone Regular 3
  • Ectosone Scalp Lotion 3
  • Elocom 18
  • Eumovate 5
  • Florone 7
  • Fluoderm 9
  • Fluolar 9
  • Fluonide 9
  • Halog 13
  • Kenalog 20
  • Lidemol 10
  • Lidex 10
  • Lyderm 10
  • Metaderm Mild 3
  • Metaderm Regular 3
  • Nerisone 8
  • Nerisone Oily 8
  • Novobetamet 3
  • Occulocort 3
  • Prevex B 3
  • Propaderm 2
  • Synalar 9
  • Synamol 9
  • Topicort 6
  • Topicort Mild 6
  • Topilene 3
  • Topisone 3
  • Topsyn 10
  • Triaderm 20
  • Trianide Mild 20
  • Trianide Regular 20
  • Valisone Scalp Lotion 3
  • Westcort 17

Other commonly used names are:

  • Beclometasone
  • Fludroxycortide
  • Ulobetasol

Note:

For quick reference, the medium to very high potency corticosteroids below are enumerated to match their brand names.

This information is applicable to all the medicines listed below:
1. Amcinonide (am-SIN-oh-nide)
2. Beclomethasone (be-kloe-METH-a-sone)*
3. Betamethasone (bay-ta-METH-a-sone)
4. Clobetasol (kloe-BAY-ta-sol)
5. Clobetasone (kloe-BAY-ta-sone)*
6. Desoximetasone (des-ox-i-MET-a-sone)
7. Diflorasone (dye-FLOR-a-sone)
8. Diflucortolone (dye-floo-KOR-toe-lone)*
9. Fluocinolone (floo-oh-SIN-oh-lone)
10. Fluocinonide (floo-oh-SIN-oh-nide)
11. Flurandrenolide (flure-an-DREN-oh-lide) (except Drenison-1/4)
12. Fluticasone (floo-TIK-a-sone)
13. Halcinonide (hal-SIN-oh-nide)
14. Halobetasol (hal-oh-BAY-ta-sol)
15. Hydrocortisone butyrate (hye-droe-KOR-ti-sone bue-TEAR-ate)
16. Hydrocortisone probutate (hye-droe-KOR-ti-soneproe-BYOE-tate)
17. Hydrocortisone valerate (hye-droe-KOR-ti-sone val-AIR-ate)
18. Mometasone (moe-MET-a-sone)
19. Prednicarbate (PRED-ni-kar-bate)
20. Triamcinolone (trye-am-SIN-oh-lone)
* Not tradable in the U.S.
† Not tradable in Canada
‡ Generic medicine may be available in the U.S.

Category

  • Anti-inflammatory, steroidal, topical
  • Corticosteroid, topical

Description

Topical corticosteroids (kor-ti-ko-STER-oyds) are used to help relieve redness, swelling, itching, and discomfort of many skin problems. These medicines are like cortisone. They belong to the general family of medicines called steroids.

These corticosteroids are available only with your doctor's prescription. Topical corticosteroids are available in the following dosage forms:

  • Topical
  • Amcinonide
    • Cream (U.S. and Canada)
    • Lotion (U.S. and Canada)
    • Ointment (U.S. and Canada)
  • Beclomethasone
    • Cream (Canada)
    • Lotion (Canada)
  • Betamethasone
    • Cream (U.S. and Canada)
    • Foam (U.S.)
    • Gel (U.S. and Canada)
    • Lotion (U.S. and Canada)
    • Ointment (U.S. and Canada)
    • Topical aerosol (U.S.)
  • Clobetasol
    • Cream (U.S. and Canada)
    • Foam (U.S.)
    • Ointment (U.S. and Canada)
    • Topical solution (U.S. and Canada)
  • Clobetasone
    • Cream (Canada)
    • Ointment (Canada)
  • Desoximetasone
    • Cream (U.S. and Canada)
    • Gel (U.S. and Canada)
    • Ointment (U.S.)
  • Diflorasone
    • Cream (U.S. and Canada)
    • Ointment (U.S. and Canada)
  • Diflucortolone
    • Cream (Canada)
    • Ointment (Canada)
  • Fluocinolone
    • Cream (U.S. and Canada)
    • Ointment (U.S. and Canada)
    • Topical solution (U.S. and Canada)
  • Fluocinonide
    • Cream (U.S. and Canada)
    • Gel (U.S. and Canada)
    • Ointment (U.S. and Canada)
    • Topical solution (U.S. and Canada)
  • Flurandrenolide
    • Cream (U.S. and Canada)
    • Lotion (U.S.)
    • Ointment (U.S. and Canada)
    • Tape (U.S. and Canada)
  • Fluticasone
    • Cream (U.S.)
    • Ointment (U.S.)
  • Halcinonide
    • Cream (U.S. and Canada)
    • Ointment (U.S. and Canada)
    • Topical solution (U.S. and Canada)
  • Halobetasol
    • Cream (U.S.)
    • Ointment (U.S.)
  • Hydrocortisone butyrate
    • Cream (U.S.)
    • Ointment (U.S.)
  • Hydrocortisone probutate
    • Cream (Canada)
  • Hydrocortisone valerate
    • Cream (U.S. and Canada)
    • Ointment (U.S. and Canada)
  • Mometasone
    • Cream (U.S. and Canada)
    • Lotion (U.S. and Canada)
    • Ointment (U.S. and Canada)
  • Prednicarbate
    • Cream (U.S.)
  • Triamcinolone
    • Cream (U.S. and Canada)
    • Lotion (U.S.)
    • Ointment (U.S. and Canada)
    • Topical aerosol (U.S.)

Before Using This Medicine

When deciding if it's worth using a medicine, the risk of taking it must be carefully weighed against the benifit it can do. This is the decision you and your doctor are to make together. Concerning corticosteroids, the following aspects should be taken into account:

Allergies—Inform your doctor if you have ever experienced any unusual or allergic reaction to corticosteroids. Also tell your doctor if you are allergic to any other substances, like foods, preservatives, dyes.

Pregnancy—When used properly, these medicines have not been shown to cause problems in humans. Studies on birth defects have not been done in humans. However, studies in animals have shown that topical corticosteroids, when applied to the skin in large amounts or used for a long time, could cause birth defects.

Breast-feeding—Topical corticosteroids have not been reported to cause problems in nursing babies when used properly. However, corticosteroids should not be applied to the breasts before nursing.

Children—Children and teenagers who must use this medicine should be checked often by their doctor since this medicine may be absorbed through the skin and can affect growth or cause other unwanted effects.

Older adults—Certain side effects may be more likely to occur in elderly patients since the skin of older adults may be naturally thin. These unwanted effects may include tearing of the skin or blood-containing blisters on the skin.

Other medicines—Although some medicines should not be used together at all, there are cases when 2 different medicines maybe used together even if an interaction might occur. In such cases, your doctor may advise you to change the dose, or other precautions may be required. Tell your health care professional if you are using any other topical prescription or nonprescription (over-the-counter [OTC]) medicine that is to be applied to the same area of the skin.

Other medical problems—The existence of other medical problems may influence the use of /topical corticosteroids. You should tell your doctor if you have any other medical problems, in particular::

  • Cataracts or
  • Glaucoma—Corticosteroids may make these medical problems worse, especially when stronger corticosteroids are used in the eye area
  • Diabetes mellitus (sugar diabetes)—Too much use of corticosteroids may cause a loss of control of diabetes by increasing blood and urine glucose. However, this is not likely to happen when topical corticosteroids are used for a short time
  • Infection or sores at the place of treatment (unless your doctor also prescribed medicine for the infection) or
  • Tuberculosis—Corticosteroids may make existing infections worse or cause new infections
  • Skin conditions that cause thinning of skin with easy bruising—Corticosteroids may make thinning of the skin worse

Proper Use of This Medicine

Be very careful not to get this medicine in your eyes. Wash your hands after using your finger to apply the medicine. If you accidentally get this medicine in your eyes, flush them with water.

Do not bandage or otherwise wrap the skin being treated unless directed to do so by your doctor.

If your doctor has ordered an occlusive dressing (airtight covering, such as kitchen plastic wrap or a special patch) to be applied over this medicine, make sure you know how to apply it. Since occlusive dressings increase the amount of medicine absorbed through your skin and the possibility of side effects, use them only as directed. If you have any questions about this, check with your doctor.

Do not use on face, groin, or armpits unless directed to do so by your doctor.

For patients using the foam form of this medicine:

  • This medicine usually comes with patient directions. Read them carefully before using this medicine.
  • Do not use near heat, near an open flame, or while smoking.

For patients using the topical aerosol form of this medicine:

  • This medicine usually comes with patient directions. Read them carefully before using this medicine.
  • It is important to avoid breathing in the vapors from the spray or getting them in your eyes. If you accidentally get this medicine in your eyes, flush them with water.
  • Do not use near heat, near an open flame, or while smoking.

For patients using flurandrenolide tape :

  • This medicine usually comes with patient directions. Read them carefully before using this medicine.

Do not use this medicine more often or for a longer time than your doctor ordered . To do so may increase the chance of absorption through the skin and the chance of side effects. In addition, too much use, especially on areas with thinner skin (for example, face, armpits, groin), may result in thinning of the skin and stretch marks or other unwanted effects.

Do not use this medicine for other skin problems without first checking with your doctor . Topical corticosteroids should not be used on many kinds of bacterial, viral, or fungal skin infections.

Dosing—The dose of topical corticosteroid will vary for different patients and products. Adhere to the orders of your doctor or the instructions on the label .

Missed dose—If your doctor has ordered you to use this medicine on a regular schedule and you miss a dose, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and apply it at the next regularly scheduled time.

Storage—To store this medicine properly, follow the instructions below:

  • Keep out of the reach of children.
  • Store away from heat and direct light.
  • Keep the medicine from freezing.
  • Do not puncture, break, or burn aerosol containers, even after they are empty.
  • Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.

Precautions While Using This Medicine

Check with your doctor if your symptoms do not improve within 1 week or if your condition gets worse.

Avoid using tight-fitting diapers or plastic pants on a child if this medicine is being used on the child's diaper area. Plastic pants or tight-fitting diapers may increase the chance of absorption of the medicine through the skin and the chance of side effects.

Side Effects of This Medicine

Alongside with its expected effects, any medicine may be the cause of some unwanted effects. Although not all of these side effects may happen, if they do happen they may require medical attention.

Consult your doctor immediately if any of the side effects from the list below occur:

Less frequent or rare

Blood-containing blisters on skin; burning and itching of skin; increased skin sensitivity (for some brands of betamethasone lotion); lack of healing of skin condition; loss of top skin layer (for tape dosage forms); numbness in fingers; painful, red or itchy, pus-containing blisters in hair follicles; raised, dark red, wart-like spots on skin, especially when used on the face; skin infection; thinning of skin with easy bruising

Additional side effects may occur if you use this medicine improperly or for a long time. Check with your doctor if any of the following side effects occur:

Rare

Acne or oily skin; backache; blurring or loss of vision (occurs gradually if certain products have been used near the eye); burning and itching of skin with pinhead-sized red blisters; eye pain (if certain products have been used near the eye); filling or rounding out of the face; increased blood pressure; irregular heartbeat; irregular menstrual periods; irritability; irritation of skin around mouth; loss of appetite; mental depression; muscle cramps, pain, or weakness; nausea; rapid weight gain or loss; reddish purple lines (stretch marks) on arms, face, legs, trunk, or groin; skin color changes; softening of skin; stomach bloating, burning, cramping, or pain; swelling of feet or lower legs; tearing of the skin; unusual bruising; unusual decrease in sexual desire or ability (in men); unusual increase in hair growth, especially on the face; unusual loss of hair, especially on the scalp; unusual tiredness or weakness; vomiting; weakness of the arms, legs, or trunk (severe); worsening of infections

Some side effects may occur that usually do not need medical attention. These side effects may disappear in the course of treatment as your body gets used to the medicine. Nevertheless, inform your doctor if any of the side effects below persist or became annoying:

Less frequent or rare—usually mild and transient

Burning, dryness, irritation, itching, or redness of skin; increased redness or scaling of skin sores; skin rash

When the foam, gel, lotion, solution, or aerosol form of this medicine is applied, a mild, temporary stinging may be expected.

Other side effects not mentioned above may also happen in some patients. If you notice any other effects, tell your doctor about it.

Additional Information

Once a drug has been approved for marketing for certain cases, experience may show that it can also be applied to treatment of some other medical problems. Although this use is not included in product labeling, topical corticosteroids may be used in certain patients with the following medical conditions:

  • Phimosis

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